Ms. St. Onge was born in Worcester MA, She grew up on college campuses as the the only child of a Physics professor and a painter. She received an M.F.A. from Massachusetts College of Art, Boston, MA

St. Onge's work focus on the the cross over of art and science and photography's abilty to distill our sense of time and curiosity. She makes pictures predominantly with an 8 x 10 view camera and considers her work a collaborative process.

Her photographs have been widely exhibited, most notably at Princeton University, University of Rhode Island, Massachusetts College of Art, Rick Wester Fine Arts and an American Institute of Architects traveling exhibitions. She has received numerous awards and residences among them a 2009 John Simon Guggenheim Fellowship, a Critical Mass Finalist Exhibition Award, Polaroid Materials Artist Support Grant and MIT graduate Fellowship. 

Her photographs are in several private and public collections; the University of New Mexico Art Museum, the Houston Museum of Fine Arts, the Cassilhaus Collection and the Guggenheim Foundation.

She been on the faculty at Clark University, Maine College of Art and The University of New Hampshire. Ms. St. Onge created and taught the University of New Hampshires's Art and Art History Dept's first online curriculum beginning in 2011. She divides her time between Durham, New Hampshire and coastal Maine.